Tirupati: In a tragic incident, a woman was killed and several injured after a speeding Innova vehicle rammed into an RTC bus in opposite direction. The incident took place near Vakulamata temple, at Mitta Gandhipuram National High Way. According to the sources, the deceased persons were identified as residents of the Dharmapuri district of Tamil Nadu. It is learnt that the Innova vehicle rammed into the RTC bus in the wrong direction and a woman died on the spot and four persons were injured severely in the accident. The injured persons were immediately shifted to a nearby hospital. The police registered a case and an investigation is underway.