After the Corona virus pandemic, it is now Monkeypox that is causing concern throughout the world. It is rapidly spreading in Western countries, especially the United States, causing concern. The first case was reported in the United Kingdom. In 12 nations, the total number of victims has already surpassed 100. The World Health Organization (WHO) has raised alarm about the spread of Monkeypox as more people fall prey to it. According to WHO, the United States, Canada, and Australia are the most impacted countries owing to Monkeypox. Monkeypox instances have also been documented in the United Kingdom, Portugal, Germany, Italy, France, Belgium, and the Netherlands. After witnessing the severe transmission of Monkeypox cases, India was notified. Union Health Minister Mansukh Mandaviya has asked officials to segregate and collect samples from suspected international flying passengers and analyse the same.