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Indian-origin scientist designs tiny 'vehicle' to drive drugs to targets

Mon, Sep 21, 2015, 02:22 PM
New Delhi, Sep 21: With the side-effects of therapy being one of the major stumbling blocks in advancing treatment for deadly diseases, a team of scientists, including one of Indian origin, has designed a "nanovehicle" that could drive ***** straight to their destinations - the diseased tissues - thereby sparing other healthy organs from any unintended effects.

Made of gold nanoparticles, the nanovehicle was found to be non-toxic when tested in cultured human cell lines, study co-author Arnab De of the Chicago-based AbbVie Bioresearch Centre told IANS in an e-mail interview.

"***** should ideally act only on diseased tissues. However, it is difficult to deliver ***** only to diseased tissues without affecting other healthy tissues. The side effects of ***** are often seen on these healthy tissues," De, a PhD from Columbia University in the City of New York, explained.

"This is a proof-of-concept study that shows that it may be possible to selectively navigate a drug to certain tissues. However, extensive animal studies need to be done to determine non-specific targeting in animals," noted De, who collaborated for the research with a team of scientists from the University of Delhi.

The research was conducted at professor Subho Mozumdar's laboratory at the University of Delhi.

Other co-authors of the study were Tanusri Nandi and Seema Garg, a student in Mozumdar's lab who played an important role in synthesising the nanoparticles.
Agency: IANS
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